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Homosynaptic plasticity : ウィキペディア英語版
Homosynaptic plasticity
Homosynaptic plasticity is one type of synaptic plasticity.〔Purves, D., Augustine, G. J., Fitzpatrick, D., Hall, W. C., LaMantia, A. S., White, L. E. (2012). Synaptic Plasticity. In Neuroscience (5th ed.) (pp. 163-182). Sunderland, Massachusetts: Sinauer Associates.〕 Homosynaptic plasticity is input-specific, meaning changes in synapse strength occur only at post-synaptic targets specifically stimulated by a pre-synaptic target.〔Byrne, J. (1997). (Synaptic Plasticity. ) In Neuroscience Online (Section 1, Chapter 7).〕 Therefore, the spread of the signal from the pre-synaptic cell is localized. Another type of synaptic plasticity, heterosynaptic plasticity, is not input-specific and differs from homosynaptic plasticity in many mechanisms.
In addition to being input-specific, the strengthening of a synapse via homosynaptic plasticity is associative, because it is dependent on the firing of a presynaptic and postsynaptic neuron closely in time. This associativity increases the chances that the postsynaptic neuron will also fire.〔Bailey, C., Giustetto, M., Huang, Y., Hawkins, R., Kandel, E. (Oct. 2000). Reviews: Is Heterosynaptic Modulation Essential for Stabilizing Hebbian Plasticity and Memory?. In Macmillan Magazines Ltd (Vol. 1). Retrieved from www.nature.com/reviews/neuroscience〕 These mechanisms are used primarily for learning and short-term memory.〔
==Overview==


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